Percutaneous coronary intervention or coronary artery bypass graft for unprotected left main coronary artery disease: the endless debate.
نویسندگان
چکیده
(Total Occlusion Study of Canada) trial (24), a substudy of the OAT study, there was a trend toward more favorable remodeling. The results of the OAT study do not prove or disprove the benefits of late revascularization in patients similar to the patients in the OAT study and certainly do not apply to the entirety of post-AMI patients. Unfortunately, despite the efforts of investigators like the OAT Investigators, only 3,560 patients have been randomized to date, and they may not be enough to draw meaningful conclusions and/or identify subgroups of patients with greatest benefit or risk from late revascularization. We thank Dr. Džavı́k and colleagues for this opportunity to clarify that our analysis was not designed to prove or disprove the findings of the OAT study, which likely applies to a minority of patients after AMI. Instead, we set out to analyze all available evidence and demonstrated the benefit of late revascularization of the IRA late after AMI.
منابع مشابه
Acute and Long Term Outcomes of Coronary Intervention in Unprotected Left Main Lesions
Introduction : Significant left main coronary artery stenosis jeopardizes the entire myocardium of the left ventricle and has the worst prognosis of any form of coronary artery disease. Coronary-artery bypass grafting (CABG) has been considered as the standard therapeutic approach for such patients. There are limited data on the safety and effectiveness of percutaneous coronary intervention (PC...
متن کاملOutcomes of coronary artery bypass grafting versus percutaneous coronary intervention with second-generation drug-eluting stents for patients with multivessel and unprotected left main coronary artery disease
OBJECTIVES To compare the efficacy and safety of percutaneous coronary intervention using second-generation drug-eluting stents with those of coronary artery bypass grafting among patients with multivessel disease and/or unprotected left main coronary artery disease in terms of mortality, myocardial infarction, repeat revascularization, and angina. BACKGROUND Although coronary artery disease ...
متن کاملEmergency intervention for unprotected left main coronary artery stenosis: case report and review of the literature.
Left main coronary artery stenosis is an important cause of symptomatic coronary artery disease, although relatively infrequent. The current guidelines recommend coronary artery bypass grafting as the first line treatment and standard of care, but percutaneous coronary intervention is likely to lead to faster reperfusion of coronary flow, avoiding the delays of a major surgical intervention. Ou...
متن کاملWhat is the best way to treat left main coronary artery disease?
umerous researchers have attempted to improve the methods of percutaneous coronary intervention (PCI), with the goal of obtaining equivalent or better long-term results compared with coronary artery bypass graft (CABG). In the beginning of the drug eluting stent (DES) era, the initial success rate was very high rate and the target lesion revascularization (TLR) of PCI was dramatically improved....
متن کاملSurgical ineligibility and mortality among patients with unprotected left main or multivessel coronary artery disease undergoing percutaneous coronary intervention.
BACKGROUND Decisions to proceed with surgical versus percutaneous revascularization for multivessel coronary artery disease are often based on subtle clinical information that may not be captured in contemporary registries. The present study sought to evaluate the association between surgical ineligibility documented in the medical record and long-term mortality among patients with unprotected ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of the American College of Cardiology
دوره 52 7 شماره
صفحات -
تاریخ انتشار 2008